Following are the combinations which indicate that the native is afflicted by Sarpa Sapa. These Yogas will result in the native not having children or losing children :
1. Rahu in the 5th house and Kuja aspecting the 5th house OR 5th house is owned by Kuja and Rahu is placed in it
2. If the 5th lord has connection to Rahu and Saturn is placed in the 5th and aspected or conjoined by Moon.
3.If Putra Karaka Guru is connected to Kuja, Rahu is placed in the lagna and 5th lord is in Dusthana
4. If 5th house is one of Rasis owned by Kuja , Rahu is placed in 5th and aspected or conjoined by Mercury.
These are the Sarpa Sapa Yogas.
There might be other combinations and placements of planets also which may lead to Childlessness or loss of children. Following are some of those :
1. If 5th lord is combust and is placed in a Dusthana or an enemy's sign aspected by a naturally malefic planet
2. If 5th house has very less number of Sarvashtaka varga Bindus
3. If Lagna, 7th lord , 5th lord and Jupiter are bereft of strength
4. If there is a Naturally malefic planet in the 5th house and the 5th lord is debilitated and doesnt have aspect of a naturally benefic planet.
5. Kuja in the 6th house and Saturn in the 4th house
6. If the 6th lord from lagna is placed in the 6th house along with Ravi and Saturn and has aspect from Mercury
7. If Saturn is placed in the 7th from lagna ,Moon is placed in the 10th and Jupiter and Ravi are conjunct
8. If Ravi is placed in the lagna and Saturn is placed in the 7th house from it
9. If Kuja,Chandra and Sukra are in the 7th from lagna
10. If Saturn is the 5th lord and is placed in Mesha in conjunction with Ravi and is aspected by Kuja
11. If Guru happens to be the 5th lord and in conjunction with Sukra is placed in the 12th from lagna and lagna is aspected by a malefic planet
12. If Chandra happens to be the 5th lord and in conjunction with Budha is placed in the 12th from lagna and Jupiter is placed in the 8th house
13. If Ravi happens to be the 5th lord and is in conjunct with a debilitated planet or has a debilitated aspect from a planet and is placed in the 12th from lagna and Jupiter is combust
